MTSS is a proactive and preventative framework that integrates data and instruction to maximize student achievement and support students' social, emotional, and behavioral needs from a strengths-based perspective. Best practices for an MTSS framework should include universal screening, evidence-based practices done with fidelity, progress monitoring, and data-based decision making. 

Well-functioning instructional practices should include high-quality Tier 1, consisting of a research-based curriculum, support all students (English learners, special education, gifted and talented, etc.), use small groups, differentiation, scaffolding, and accommodations. Tiers 2 and 3 should use evidence-based interventions and supplement Tier 1. Fidelity of MTSS implementation is critical throughout Tiers 1, 2, and 3. Campus-level MTSS teams review and use instructional data, combined with staff members' expertise, to make decisions with the students’ best interests in mind, aligning instruction and support to match individual student needs.